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- CEL file information
- February 25, 2026
A .CEL file is interpreted differently across contexts, but in genomics work it is typically the Affymetrix/Thermo Fisher microarray output containing raw intensity measurements from the chip’s many probe spots, recorded after scanning the hybridized array and mapped by coordinates or probe indices with related metadata; these raw values require downstream processing—background correction, normalization, summarization—using R/Bioconductor packages such as oligo and informed by supporting files like .CDF and .CHP.
In animation work, “cel” refers to traditional celluloid sheets, and a CEL file often stands for one rasterized frame or layer—usually with transparency—to be stacked over background art, frequently appearing in sequences such as `walk_001.cel` and accompanied by palette or auxiliary image files; because different programs defined CEL formats differently, some open easily in standard editors while others require original tools, and certain games also use `.CEL` as a custom sprite/texture format, making the extension unreliable by itself, so identifying it quickly involves checking its source, surrounding assets, naming conventions, file size, and inspecting a snippet in a text/hex viewer.
If you are you looking for more in regards to CEL data file look into the page. In 2D animation, a “cel” comes from physical cel layers used in classic animation showing one slice of artwork placed over a background, and modern digital animation preserves the layered approach; a CEL file therefore acts as a raster image representing a single layer or frame—like an arm movement, facial expression, or effects element—with alpha transparency so it stacks seamlessly with other layers.
Because “.CEL” has shifted across various tools, a CEL file may be palette-based, tool-specific, or dependent on an external palette, which is why they often appear in art-production folders like `frames` or `cels` in sequences such as `idle_001.cel`; opening them can be simple or may need the original application, and the CEL itself is just one raster frame/layer that gets composited with others during animation.
To classify a .CEL file quickly, the most reliable move is to examine where it came from, since genomic sources typically point to microarray CELs, whereas art/game pipelines suggest animation layers or asset formats; look at nearby files for confirmation—microarray sets include .CDF or .CHP, while animation/game folders contain many numbered CELs and palette files—and then compare file size, count, and a small header peek in a text/hex viewer to spot either readable array metadata or primarily binary graphics/asset data.
“.CEL isn’t a single universal standard” highlights that the letters don’t guarantee a specific file type, because different companies and industries have reused “.cel” for unrelated purposes, treating it as a simple filename suffix rather than a format with a shared specification; that’s why an Affymetrix CEL can store probe-intensity data, an animation CEL can be a raster frame with transparency, and a game CEL can be a proprietary sprite/resource file—same extension but entirely different “languages” inside, making context or header inspection necessary to know which tool can open it.